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Sensitive cilia set up the kidney

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An inherited form of kidney disease results from defects in the cilium. Mouse knockout experiments now explore how cilia help guide the organ into the right shape—and hint that these tiny antennae may also help regulate food intake (pages 1490–1495).

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Figure 1: A 'developmental switch' sets the rate of cyst formation in the kidney.

Kim Caesar

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Kim, E., Walz, G. Sensitive cilia set up the kidney. Nat Med 13, 1409–1411 (2007). https://doi.org/10.1038/nm1207-1409

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