Dietary lipids seem to activate a Toll-like receptor, which is better known for its defense against infectious pathogens. The findings suggest that the resulting inflammatory response may link obesity with type 2 diabetes.
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Ann Thomson
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Tschöp, M., Thomas, G. Fat fuels insulin resistance through Toll-like receptors. Nat Med 12, 1359–1361 (2006). https://doi.org/10.1038/nm1206-1359
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DOI: https://doi.org/10.1038/nm1206-1359
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