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West Nile virus: crossing the blood-brain barrier

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A study in mice traces the path of West Nile virus into the brain. Viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier (pages 1366–1373).

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Figure 1: West Nile crossing.

Deborah Maizels

References

  1. Ballabh, P., Braun, A. & Nedergaard, M. Neurobiol. Dis. 16, 1–13 (2004).

    Article  CAS  Google Scholar 

  2. Wang, T. & Fikrig, E. Nat. Med. 10, 1366–1373 (2004).

    Article  CAS  Google Scholar 

  3. Granwehr, B.P. et al. Lancet Infect. Dis. 4, 547–556 (2004).

    Article  Google Scholar 

  4. Diamond, M.S., Shrestha, B., Mehlhop, E., Sitati, E. & Engle, M. Viral Immunol. 16, 259–278 (2003).

    Article  CAS  Google Scholar 

  5. Boehme, K.W. & Compton, T. J. Virol. 78, 7867–7873 (2004).

    Article  CAS  Google Scholar 

  6. Iwasaki, A. & Medzhitov, R. Nat. Immunol. 5, 987–995 (2004).

    CAS  PubMed  Google Scholar 

  7. de Vries, H.E. et al. J. Neuroimmunol. 64, 37–43 (1996).

    Article  CAS  Google Scholar 

  8. Fiala, M. et al. Mol. Med. 3, 553–564 (1997).

    Article  CAS  Google Scholar 

  9. Edelmann, K.H. et al. Virology 322, 231–238 (2004)

    Article  CAS  Google Scholar 

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Diamond, M., Klein, R. West Nile virus: crossing the blood-brain barrier. Nat Med 10, 1294–1295 (2004). https://doi.org/10.1038/nm1204-1294

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