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Eye vessels saved by rescuing their pericyte partners

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High blood sugar can lead to diabetic retinopathy and subsequent blindness. Glucose is now found to quench a growth factor that keeps pericytes alive. Without these key support cells, the retinal vasculature degenerates (pages 1298–1306).

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Figure 1: Interactions between endothelial cells and pericytes in the eye.

Marina Corral

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Authors and Affiliations

  1. David Antonetti is at the Department of Cellular and Molecular Physiology and Ophthalmology, Penn State College of Medicine Hershey, PA USA.,

    David Antonetti

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  1. David Antonetti
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Correspondence to David Antonetti.

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Antonetti, D. Eye vessels saved by rescuing their pericyte partners. Nat Med 15, 1248–1249 (2009). https://doi.org/10.1038/nm1109-1248

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