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Good and bad lipids in the lung

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Bacterial pneumonia can be a life-threatening disease that causes lung injury. A new study shows that accumulation of a phospholipid in the lung fluid in mice and humans worsens gas exchange during the microbial infection (pages 1120–1127). Clearance of this lipid may improve lung function during infection.

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Figure 1: Surfactant homeostasis and proposed new model of lung dysfunction by cardiolipin in pneumonia.

Marina Corral

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Authors and Affiliations

  1. Kong Chen and Jay K. Kolls are in the Department of Genetics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.,

    Kong Chen & Jay K Kolls

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  1. Kong Chen
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  2. Jay K Kolls
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Correspondence to Jay K Kolls.

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The authors declare no competing financial interests.

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Chen, K., Kolls, J. Good and bad lipids in the lung. Nat Med 16, 1078–1079 (2010). https://doi.org/10.1038/nm1010-1078

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