Skip to main content

Advertisement

SpringerLink
Log in

Merging mitochondria for neuronal survival

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

Loss of mitochondrial fusion causes a rapid degeneration of cerebellar Purkinje cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Mitochondrial abnormalities in degenerating Mfn2-deficient Purkinje cells.

References

  1. Chan, D., Frank, S. & Rojo, M. Cell Death Differ. 13, 680–684 (2006).

    Article  CAS  Google Scholar 

  2. Chen, H. et al. J. Cell Biol. 160, 189–200 (2003).

    Article  CAS  Google Scholar 

  3. Cipolat, S., Martins de Brito, O., Dal Zilio, B. & Scorrano, L. Proc. Natl. Acad. Sci. USA 101, 15927–15932 (2004).

    Article  CAS  Google Scholar 

  4. Delettre, C. et al. Nat. Genet. 26, 207–210 (2000).

    Article  CAS  Google Scholar 

  5. Alexander, C. et al. Nat. Genet. 26, 211–215 (2000).

    Article  CAS  Google Scholar 

  6. Zuchner, S. et al. Nat. Genet. 36, 449–451 (2004).

    Article  Google Scholar 

  7. Chen, H., McCaffery, J.M. & Chan, D.C. Cell 130, 548–562 (2007).

    Article  CAS  Google Scholar 

  8. Alavi, M.V. et al. Brain 130, 1029–1042 (2007).

    Article  Google Scholar 

  9. Davies, V.J. et al. Hum. Mol. Genet. 16, 1307–1318 (2007).

    Article  CAS  Google Scholar 

  10. D'Aurelio, M. et al. Hum. Mol. Genet. 13, 3171–3179 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Giovanni Manfredi and M. Flint Beal are in the Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA. gim2004@med.cornell.edu fbeal@med.cornell.edu,

    Giovanni Manfredi & M Flint Beal

Authors
  1. Giovanni Manfredi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M Flint Beal
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Manfredi, G., Beal, M. Merging mitochondria for neuronal survival. Nat Med 13, 1140–1141 (2007). https://doi.org/10.1038/nm1007-1140

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm1007-1140

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation