Stem cells in mismatched placental blood can safely reconstitute hemopoiesis in children.
References
Broxmeyer, H.E. et al. Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc. Natl. Acad. Sri. USA 86, 3828–3832 (1989).
Gluckman, E. et al. Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical cord blood from a HLA-identical sibling. N. Engl. J. Med. 321, 1174–1178 (1989).
Kurtzberg, J. et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N. Engl. J. Med. 335, 157–166(1996).
Laporte, J. et al. Cord-blood transplantation from an unrelated donor in an adult with chronic myelogenous leukemia. N. Engl. J. Med. 335, 167–170 (1996).
Appelbaum, F.R. et al. Allogeneic marrow transplantation for chronic myeloid leukemia. Med. Oncol. 11, 69–74 (1994).
Kohn, D.B. et al. Engraftment of gene-modified umbilical cord blood in neonates with adenosine deaminase deficiency. Nature Med. 1, 1017–1023 (1995).
Butler, D. US company comes under fire over patent on umbilical cord cells. Nature 382, 99 (1996).
Gluckman, E., O'Reilly, R., Wagner, J. & Rubinstein, P. Patents versus transplants. Nature 382, 108 (1996).
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Brenner, M. Placental blood transplant: Who will benefit?. Nat Med 2, 969–970 (1996). https://doi.org/10.1038/nm0996-969
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DOI: https://doi.org/10.1038/nm0996-969
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