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The clot thickens—oxidized lipids and thrombosis

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Oxidized products of low-density lipoproteins (LDLs) activate platelets through CD36, demonstrating a link between deregulated lipoprotein levels, oxidative stress and thrombosis (pages 1086–1095).

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Figure 1: Role of oxidized products of LDL in promoting platelet activation and thrombus formation in vivo.

Katie Ris-Vicari

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Authors and Affiliations

  1. Shaun P. Jackson is at the Australian Centre for Blood Diseases, Monash University, Melbourne, Australia. shaun.jackson@med.monash.edu.au,

    Shaun P Jackson

  2. Anna C. Calkin is at the Baker Heart Research Institute, Alfred Medical Research & Education Precinct, Melbourne, Australia. anna.calkin@baker.edu.au,

    Anna C Calkin

Authors
  1. Shaun P Jackson
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  2. Anna C Calkin
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The authors declare no competing financial interests.

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Jackson, S., Calkin, A. The clot thickens—oxidized lipids and thrombosis. Nat Med 13, 1015–1016 (2007). https://doi.org/10.1038/nm0907-1015

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