Skip to main content

Advertisement

Log in

Microbes adapt to inner space

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

The human gastric bacterium Helicobacter pylori can acquire cholesterol from its host and enzymatically alter the molecule to counteract the immune system. The finding reveals yet another strategy used by successful microbial colonizers to evade immunity. Do such strategies make the microbe more like us (pages 1030–1038)?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Levels of interaction between hosts and coevolved residential microbes.

Kim Caesar

References

  1. Wunder, C. et al. Nat. Med 12, 1030–1038 (2006).

    Article  CAS  Google Scholar 

  2. Kelly, D., Conway, S. & Aminov, R. Trends lmmunol. 26, 326–333 (2005).

    Article  CAS  Google Scholar 

  3. Briles, D.E., Novak, L., Hotomi, M., van Ginkel, F.W. & King, J. Infect. Immun. 73, 6945–6951 (2005).

    Article  CAS  Google Scholar 

  4. Gill, S.R. et al. Science 312, 1355–1359 (2006).

    Article  CAS  Google Scholar 

  5. Bik, E.M. et al. Proc. Natl. Acad. Sci. USA 103, 732–737 (2006).

    Article  CAS  Google Scholar 

  6. Falush, D. et al. Science 299, 1582–1585 (2003).

    Article  CAS  Google Scholar 

  7. Blaser, M.J. & Atherton, J. J. Clin. Invest. 113, 321–333 (2004).

    Article  CAS  Google Scholar 

  8. Pérez-Pérez, G.I., Shepherd, V.L., Morrow, J.D. & Blaser, M.J. Infect. Immun. 63, 1183–1187 (1995).

    PubMed  PubMed Central  Google Scholar 

  9. Gebert, B., Fischer, W., Weiss, E., Hoffmann, R. & Haas, R. Science 301, 1099–1102 (2003).

    Article  CAS  Google Scholar 

  10. Amieva, M.R. et al. Science 300, 1430–1434 (2003).

    Article  CAS  Google Scholar 

  11. Wirth, H.P. et al. FASEB J. 20, 1534–1536 (2006).

    Article  CAS  Google Scholar 

  12. Aras, R.A. et al. J. Exp. Med. 198, 1349–1360 (2003).

    Article  CAS  Google Scholar 

  13. Blaser, M.J. & Kirschner, D. Proc. Natl. Acad. Sci. USA 96, 8359–8364 (1999).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Blaser, M. Microbes adapt to inner space. Nat Med 12, 994–996 (2006). https://doi.org/10.1038/nm0906-994

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0906-994

  • Springer Nature America, Inc.

This article is cited by

Navigation