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TZDs and diabetes: testing the waters

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The use of thiazolidinediones, drugs for type 2 diabetes that may also be useful for other chronic inflammatory disorders, is limited by fluid retention. Research in mice identifies a mechanism for this side effect and introduces a potential remedy (pages 861–866).

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Figure 1: Lowering the water.

Katie Ris

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Authors and Affiliations

  1. Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, 63110, Missouri, USA

    Clay F Semenkovich

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  1. Clay F Semenkovich
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Semenkovich, C. TZDs and diabetes: testing the waters. Nat Med 11, 822–824 (2005). https://doi.org/10.1038/nm0805-822

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