Two receptors have now been identified for the virus behind severe hand, foot and mouth disease (pages 794–797 and 798–801).
References
Fan, Y. et al. J. Clin. Microbiol. published online, doi:10.1128/JCM.00563-09 (13 May 2009).
Huang, C.C. et al. N. Engl. J. Med. 341, 936–942 (1999).
Yamayoshi, S. et al. Nat. Med. 15, 798–801 (2009).
Nishimura, Y. et al. Nat. Med. 15, 794–797 (2009).
Melnick, J.L. Rev. Infect. Dis. 6 Suppl 2, S387–S390 (1984).
Eckhardt, E.R. et al. J. Biol. Chem. 281, 4348–4353 (2006).
Vishnyakova, T.G. et al. Proc. Natl. Acad. Sci. USA 103, 16888–16893 (2006).
Philips, J.A., Rubin, E.J. & Perrimon, N. Science 309, 1251–1253 (2005).
McEver, R.P. & Cummings, R.D. J. Clin. Invest. 100, 485–491 (1997).
Lin, T.Y., Hsia, S.H., Huang, Y.C., Wu, C.T. & Chang, L.Y. Clin. Infect. Dis. 36, 269–274 (2003).
Marsh, M. & Helenius, A. Cell 124, 729–740 (2006).
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Patel, K., Bergelson, J. Receptors identified for hand, foot and mouth virus. Nat Med 15, 728–729 (2009). https://doi.org/10.1038/nm0709-728
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DOI: https://doi.org/10.1038/nm0709-728
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