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Glial cell line–derived neurotrophic factor induces neuronal sprouting in human brain

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Figure 1: UPDRS-III scores, 18F-dopa uptake and neuropathological findings.

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Acknowledgements

We thank C. Redman, R. Quilty, T. McLaren, M. Jennings and R. Barber for technical assistance. Amgen, Inc. supplied the GDNF for this trial.

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Authors and Affiliations

  1. Department of Neuropathology, Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, BS16 1LE, UK

    Seth Love

  2. Department of Neurosurgery, Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, BS16 1LE, UK

    Puneet Plaha, Nikunj K Patel & Steven S Gill

  3. MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, W12 0NN, UK

    Gary R Hotton & David J Brooks

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  1. Seth Love
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  2. Puneet Plaha
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  5. David J Brooks
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  6. Steven S Gill
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Love, S., Plaha, P., Patel, N. et al. Glial cell line–derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 11, 703–704 (2005). https://doi.org/10.1038/nm0705-703

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