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Interleukin-33 safeguards neutrophils in sepsis

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Cytokines have a fundamental role in orchestrating innate immune responses to bacterial infections. Interleukin-33 (IL-33) is now shown to protect from sepsis by promoting neutrophil influx into the focus of infection (pages 708–712).

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Figure 1: IL-33 promotes the migration of neutrophils into the focus of infection.

Kimberly Caesar

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Authors and Affiliations

  1. Department of Medicine, Thierry Roger and Thierry Calandra are in the Infectious Diseases Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.,

    Thierry Roger & Thierry Calandra

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  1. Thierry Roger
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  2. Thierry Calandra
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Correspondence to Thierry Calandra.

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Roger, T., Calandra, T. Interleukin-33 safeguards neutrophils in sepsis. Nat Med 16, 638–639 (2010). https://doi.org/10.1038/nm0610-638

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