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mTOR tells the brain that the body is hungry

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The multitasking signaling protein mTOR integrates nutritional and hormonal cues in the brain, modulating feeding and body weight.

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Figure 1: Converting metabolic signals into anorectic (appetite-suppressing) responses in the hypothalamus.

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Authors and Affiliations

  1. Division of Endocrinology, Department of Medicine, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, 02215, Massachusetts, USA

    Barbara B Kahn

  2. Departments of Medicine and Molecular and Integrative Physiology, University of Michigan, Ann Arbor, 48109, Michigan, USA

    Martin G Myers Jr.

Authors
  1. Barbara B Kahn
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  2. Martin G Myers Jr.
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Kahn, B., Myers, M. mTOR tells the brain that the body is hungry. Nat Med 12, 615–617 (2006). https://doi.org/10.1038/nm0606-615

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