Skip to main content

Advertisement

SpringerLink
Log in

Fighting off pain with resolvins

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

Pain caused by chronic inflammation is a serious health problem. But the currently available analgesic drugs cause major side effects when taken long term. A new study points to a class of molecules, resolvins, which not only provide analgesia and are well tolerated but may also reduce inflammation (pages 592–597).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Resolvins alleviate pain caused by inflammation, as well as the inflammation itself.

Kimberly Caesar

References

  1. Xu et al. Nat. Med. 16, 597–592 (2010).

    Article  Google Scholar 

  2. Mukherjee, D., Nissen, S.E. & Topol, E.J. J. Am. Med. Assoc. 286, 954–959 (2001).

    Article  CAS  Google Scholar 

  3. Noble, M. et al. Cochrane Database Syst. Rev. CD006605 (2010).

  4. Serhan, C.N. et al. J. Exp. Med. 196, 1025–1037 (2002).

    Article  CAS  Google Scholar 

  5. Serhan, C.N., Chiang, N. & Van Dyke, T.E. Nat. Rev. Immunol. 8, 349–361 (2008).

    Article  CAS  Google Scholar 

  6. Turner, D., Zlotkin, S.H., Shah, P.S. & Griffiths, A.M. Cochrane Database Syst. Rev. CD006320 (2009).

  7. Anandan, C., Nurmatov, U. & Sheikh, A. Allergy 64, 840–848 (2009).

    Article  CAS  Google Scholar 

  8. Goldberg, R.J. & Katz, J. Pain 129, 210–223 (2007).

    Article  CAS  Google Scholar 

  9. Nixon, R., Bansback, N. & Brennan, A. Rheumatology (Oxford) 46, 1140–1147 (2007).

    Article  CAS  Google Scholar 

  10. Beyreuther, B.K., Geis, C., Stöhr, T. & Sommer, C. Neuropharmacology 52, 1312–1317 (2007).

    Article  CAS  Google Scholar 

  11. Ziegler, D. et al. Diabetes Care 33, 839–841 (2010).

    Article  CAS  Google Scholar 

  12. Birklein, F. & Kingery, W.S. Pain 142, 177–178 (2009).

    Article  CAS  Google Scholar 

  13. Birklein, F. & Schmelz, M. Neurosci. Lett. 437, 199–202 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Claudia Sommer is in the Department of Neurology of the University of Würzburg, Würzburg, Germany,

    Claudia Sommer

  2. Frank Birklein is at the University Medical Centre Mainz, Mainz, Germany.,

    Frank Birklein

Authors
  1. Claudia Sommer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Frank Birklein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Claudia Sommer.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sommer, C., Birklein, F. Fighting off pain with resolvins. Nat Med 16, 518–520 (2010). https://doi.org/10.1038/nm0510-518

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0510-518

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation