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C75 inhibits food intake by increasing CNS glucose metabolism

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Figure 1: Models in which CNS reliance on glucose metabolism is reduced, and effects of C75 are attenuated.

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Acknowledgements

These studies were supported by National Institutes of Health grants DK54890 and DK17844 and by Procter & Gamble. This work was approved by the University of Cincinnati Institutional Animal Care and Use Committee.

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Authors and Affiliations

  1. Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

    Matthew D. Wortman, Deborah J. Clegg, Stephen C. Woods & Randy J. Seeley

  2. Department of Endocrinology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

    David D'Alessio

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  1. Matthew D. Wortman
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  2. Deborah J. Clegg
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  3. David D'Alessio
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  4. Stephen C. Woods
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  5. Randy J. Seeley
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Correspondence to Matthew D. Wortman.

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Competing interests

Our lab receives funds from an unrestricted education grant from Proctor & Gamble.

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Wortman, M., Clegg, D., D'Alessio, D. et al. C75 inhibits food intake by increasing CNS glucose metabolism. Nat Med 9, 483–485 (2003). https://doi.org/10.1038/nm0503-483

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