Skip to main content
Log in

The shear stress of keeping arteries clear

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

The force exerted by blood as it flows through the vessels influences the development of atherosclerosis. An understanding of how disturbed flow leads to disease is now emerging.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Stress and of the endothelial cell.

Katherine Ris

References

  1. Glagov, S., Zarins, C., Giddens, D.P. & Ku, D.N. Arch. Pathol. Lab. Med. 112, 1018–1031 (1988).

    CAS  PubMed  Google Scholar 

  2. Davies, P.F. Physiol. Rev. 75, 519–560 (1995).

    Article  CAS  Google Scholar 

  3. Yamawaki, H., Pan, S., Lee, R.T. & Berk, B.C. J. Clin. Invest. 115, 733–738 (2005).

    Article  CAS  Google Scholar 

  4. Blankenberg, S., Barbaux, S. & Tiret, L. Atherosclerosis 170, 191–203 (2003).

    Article  CAS  Google Scholar 

  5. Tricot, O. et al. Circulation 101, 2450–2543 (2000).

    Article  CAS  Google Scholar 

  6. Stoneman, V.E. & Bennett, M.R. Clin. Sci. (Lond.) 107, 343–354 (2004).

    Article  CAS  Google Scholar 

  7. Izumi, Y. et al. Circulation 108, 2812–2818 (2003).

    Article  CAS  Google Scholar 

  8. Levonen, A.L. et al. Antioxid. Redox. Signal 3, 215–229 (2001).

    Article  CAS  Google Scholar 

  9. Takeshita, S., Inoue, N., Ueyama, T., Kawashima, S. & Yokoyama, M. Biochem. Biophys. Res. Commun. 273, 66–71 (2000).

    Article  CAS  Google Scholar 

  10. Dimmeler, S., Hermann, C., Galle, J. & Zeiher, A.M. Arterioscler. Thromb. Vasc. Biol. 19, 656–664 (1999).

    Article  CAS  Google Scholar 

  11. Park, H.S. et al. J. Biol. Chem. 279, 7584–7590 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Harrison, D. The shear stress of keeping arteries clear. Nat Med 11, 375–376 (2005). https://doi.org/10.1038/nm0405-375

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0405-375

  • Springer Nature America, Inc.

This article is cited by

Navigation