Identification of drug targets in M. tuberculosis is a challenge for bench science. High-throughput mutagenesis with transposons together with microarray-based genome and transcriptome profiling has begun to meet this challenge.
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Lamichhane, G., Bishai, W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nat Med 13, 280–282 (2007). https://doi.org/10.1038/nm0307-280
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DOI: https://doi.org/10.1038/nm0307-280
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