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Cloaked virus slips between cells

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A common retrovirus encases itself in an extracellular matrix, enabling its transfer between T4 cells. The discovery of this new mode of infectivity has the potential to lead to new ways to combat the virus, human T cell leukemia virus type 1 (HTLV-1), which is associated with cancers and inflammatory disorders (pages 83–89).

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Figure 1: Cell-to-cell transmission of HTLV-1 by extracellular viral assemblies.

Katie Vicari

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Authors and Affiliations

  1. Kathryn S. Jones is in the Basic Science Program, Science Applications International Corporation-Frederick, Inc., National Cancer Institute-Frederick, Frederick, Maryland, USA.,

    Kathryn S Jones

  2. Departments of Veterinary Biosciences and Molecular Virology, Patrick L. Green is at the Center for Retrovirus Research, Immunology, and Medical Genetics, The Ohio State University, Columbus, Ohio, USA.,

    Patrick L Green

Authors
  1. Kathryn S Jones
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  2. Patrick L Green
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Correspondence to Kathryn S Jones.

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Jones, K., Green, P. Cloaked virus slips between cells. Nat Med 16, 25–27 (2010). https://doi.org/10.1038/nm0110-25

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