Skip to main content

Advertisement

SpringerLink
Log in

Opening the gateway to tumors

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

T cells can turn back cancer, but they don't always reach tumor cells in sufficient numbers to do so. A close look at the cells of tumor blood vessels suggests a way to boost T cell migration in individuals with cancer (pages 28–36).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Blocking the endothelin B receptor (ETBR) increases lymphocyte infiltration of tumors.

Katie Ris-Vicari

References

  1. Buckanvich, R.J. et al. Nat. Med. 14, 28–36 (2008).

    Article  Google Scholar 

  2. Galon, J. et al. Science 313, 1960–1964 (2006).

    Article  CAS  Google Scholar 

  3. Zhang, L. et al. N. Engl. J. Med. 348, 203–213 (2003).

    Article  CAS  Google Scholar 

  4. Coussens, L.M. & Werb, Z. Nature 420, 860–867 (2002).

    Article  CAS  Google Scholar 

  5. Nelson, J. et al. Nat. Rev. Cancer 3, 110–116 (2003).

    Article  CAS  Google Scholar 

  6. Kubes, P., Suzuki, M. & Granger, D.N. Proc. Natl. Acad. Sci. USA 88, 4651–4655 (1991).

    Article  CAS  Google Scholar 

  7. Monsurro, V. et al. J. Immunol. 166, 5817–5825 (2001).

    Article  CAS  Google Scholar 

  8. Morgan, R.A. et al. Science 314, 126–129 (2006).

    Article  CAS  Google Scholar 

  9. Rosenberg, S.A., Yang, J.C. & Restifo, N.P. Nat. Med. 10, 909–915 (2004).

    Article  CAS  Google Scholar 

  10. Kirkby, N.S., Hadoke, P.W., Bagnall, A.J. & Webb, D.J. Br. J. Pharmacol. published online, doi:10.1038/sj.bjp.0707516 (29 October 2007).

Download references

Author information

Authors and Affiliations

  1. Michael H. Kershaw is in the Cancer Immunology Research Program, Peter MacCallum Cancer Centre, St. Andrews Place, Melbourne, Victoria 3002, Australia. michael.kershaw@petermac.org,

    Michael H Kershaw

Authors
  1. Michael H Kershaw
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kershaw, M. Opening the gateway to tumors. Nat Med 14, 13–14 (2008). https://doi.org/10.1038/nm0108-13

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0108-13

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation