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Autoimmunity and apoptosis: refusing to go quietly

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Apoptosis results in the oxidation of membrane lipids on the dying cell. Newly identified oxidized lipids play a dual role: they contribute to the recognition and phagocytosis of dying cells, but may also spur antibody production and inflammation.

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Figure 1: Tipping the balance.

Kimberly Caesar

References

  1. Chang, M.K. et al. J. Exp. Med. 200, 1359–1370 (2004).

    Article  CAS  Google Scholar 

  2. Ren, Y., Silverstein, R.L., Allen, J. & Savill, J. J. Exp. Med. 181, 1857–1862 (1995)

    Article  CAS  Google Scholar 

  3. Fadok, V.A. et al. J. Clin. Invest. 101, 890–898 (1998).

    Article  CAS  Google Scholar 

  4. Huynh, M.L., Fadok, V.A. & Henson, P.M. J. Clin. Invest. 109, 41–50 (2002).

    Article  CAS  Google Scholar 

  5. Kagan, V.E. et al. Am. J. Physiol. Lung Cell Mol. Physiol. 285, L1–L17 (2003).

    Article  CAS  Google Scholar 

  6. Shi, Y., Evans, J.E. & Rock, K.L. Nature 425, 516–521 (2003).

    Article  CAS  Google Scholar 

  7. Mevorach, D., Mascarenhas, J.O., Gershov, D. & Elkon, K.B. J. Exp. Med. 188, 2313–2320 (1998).

    Article  CAS  Google Scholar 

  8. Lauber, K. et al. Cell 113, 717–730 (2003).

    Article  CAS  Google Scholar 

  9. Gershov, D., Kim, S., Brot, N. & Elkon, K.B. J. Exp. Med. 192, 1353–1364 (2000).

    Article  CAS  Google Scholar 

  10. Kim, S.J., Gershov, D., Ma, X., Brot, N. & Elkon, K.B. J. Exp. Med. 196, 655–665 (2002).

    Article  CAS  Google Scholar 

  11. Sigal, N.H., Gearhart, P.J. & Klinman, N.R. J. Immunol. 114, 1354–1358 (1975).

    CAS  PubMed  Google Scholar 

  12. Chang, M.K. et al. Proc. Natl. Acad. Sci. USA 96, 6353–6358 (1999).

    Article  CAS  Google Scholar 

  13. Binder, C.J. et al. Nat. Med. 9, 736–743 (2003).

    Article  CAS  Google Scholar 

  14. Aprahamian, T. et al. J. Exp. Med. 199, 1121–1131 (2004).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, National Jewish Medical and Research Center, Denver, 80206, Colorado, USA

    Donna L Bratton & Peter M Henson

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  1. Donna L Bratton
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  2. Peter M Henson
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Bratton, D., Henson, P. Autoimmunity and apoptosis: refusing to go quietly. Nat Med 11, 26–27 (2005). https://doi.org/10.1038/nm0105-26

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