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Noncoding RNAs as effective markers in cancer-care management

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Two recent studies show that 'silent' variants can modulate regulatory circuits, including those in noncoding RNAs, affecting cancer predisposition and drug sensitivity.

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Figure 1: Single-nucleotide variants in noncoding RNAs influence cancer susceptibility and drug sensitivity.

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Acknowledgements

M.H. and I.R. are supported by the European Research Council Starting Grant 281877 and the Spanish Ministry of Science Grant BFU2014-58027-R.

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Authors and Affiliations

  1. Department of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of Navarra, Pamplona, Spain

    Ivan Raimondi & Maite Huarte

  2. Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain

    Ivan Raimondi & Maite Huarte

Authors
  1. Ivan Raimondi
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  2. Maite Huarte
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Correspondence to Maite Huarte.

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The authors declare no competing financial interests.

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Raimondi, I., Huarte, M. Noncoding RNAs as effective markers in cancer-care management. Nat Med 23, 1122–1123 (2017). https://doi.org/10.1038/nm.4423

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