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A microbial protein that alleviates metabolic syndrome

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A recent study shows that pasteurization of Akkermansia muciniphila enhances the bacterium's ability to reduce fat mass and metabolic syndrome in mice with diet-induced obesity, and that Amuc_1100*, a thermostable outer-membrane protein of A. muciniphila, can reproduce these beneficial effects.

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Figure 1: Pasteurized Akkermansia muciniphila and its outer-membrane protein Amuc_1100* improve gut-barrier integrity and metabolic syndrome in mice with diet-induced obesity.

Marina Corral Spence/Springer Nature

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Authors and Affiliations

  1. Fernando Forato Anhê and André Marette are in the Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Québec, Canada, and the Institute of Nutrition and Functional Foods, Laval University, Québec, Canada.,

    Fernando Forato Anhê & André Marette

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  1. Fernando Forato Anhê
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  2. André Marette
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Correspondence to André Marette.

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Anhê, F., Marette, A. A microbial protein that alleviates metabolic syndrome. Nat Med 23, 11–12 (2017). https://doi.org/10.1038/nm.4261

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