Skip to main content
SpringerLink
Log in

A liquid biopsy for cancer immunotherapy

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

Human T cells that target tumor-specific mutations are attractive for cancer immunotherapy, but obtaining these T cells is challenging. A new study shows that tumor mutation–specific T cells can be isolated from the peripheral blood of patients with melanoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Tapping the blood for cancer immunotherapy.

References

  1. Rosenberg, S.A. & Restifo, N.P. Science 348, 62–68 (2015).

    Article  CAS  Google Scholar 

  2. Schumacher, T.N. & Schreiber, R.D. Science 348, 69–74 (2015).

    Article  CAS  Google Scholar 

  3. van Rooij, N. et al. J. Clin. Oncol. 31, e439–e442 (2013).

    Article  Google Scholar 

  4. Rizvi, N.A. et al. Science 348, 124–128 (2015).

    Article  CAS  Google Scholar 

  5. Gros, A. et al. Nat. Med. 22, 433–438 (2016).

    Article  CAS  Google Scholar 

  6. Gros, A. et al. J. Clin. Invest. 124, 2246–2259 (2014).

    Article  CAS  Google Scholar 

  7. Zanetti, M. J. Immunol. 194, 2049–2056 (2015).

    Article  CAS  Google Scholar 

  8. Linnemann, C. et al. Nat. Med. 21, 81–85 (2015).

    Article  CAS  Google Scholar 

  9. Tran, E. et al. Science 344, 641–645 (2014).

    Article  CAS  Google Scholar 

  10. Haber, D.A. & Velculescu, V.E. Cancer Discov. 4, 650–661 (2014).

    Article  CAS  Google Scholar 

  11. Lohr, J.G. et al. Nat. Biotechnol. 32, 479–484 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ton N. Schumacher and Wouter Scheper are in the Division of Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.,

    Ton N Schumacher & Wouter Scheper

Authors
  1. Ton N Schumacher
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wouter Scheper
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ton N Schumacher.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Schumacher, T., Scheper, W. A liquid biopsy for cancer immunotherapy. Nat Med 22, 340–341 (2016). https://doi.org/10.1038/nm.4074

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm.4074

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation