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Deriving functional beige fat from capillaries

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In a recent study, beige adipocytes were derived from the capillaries of human subcutaneous adipose tissue. When implanted into mice, these cells enhanced glucose tolerance, thus providing evidence for their potential therapeutic use.

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Figure 1: Beige adipocytes subcutaneously transplanted into mice improved glucose homoeostasis.

Marina Corral Spence/Nature Publishing Group

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Authors and Affiliations

  1. Vanessa Pellegrinelli and Antonio Vidal-Puig are at the University of Cambridge Metabolic Research Laboratories, Wellcome Trust–Medical Research Council (MRC) Institute of Metabolic Science, University of Cambridge, Cambridge, UK.,

    Vanessa Pellegrinelli & Antonio Vidal-Puig

  2. Antonio Vidal-Puig is also affiliated with the Wellcome Trust Sanger Institute, Cambridge, UK.,

    Antonio Vidal-Puig

Authors
  1. Vanessa Pellegrinelli
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  2. Antonio Vidal-Puig
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Corresponding authors

Correspondence to Vanessa Pellegrinelli or Antonio Vidal-Puig.

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The authors declare no competing financial interests.

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Pellegrinelli, V., Vidal-Puig, A. Deriving functional beige fat from capillaries. Nat Med 22, 234–236 (2016). https://doi.org/10.1038/nm.4056

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