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Personalizing pancreatic cancer organoids with hPSCs

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A new study using human pluripotent stem cell (hPSC)-derived human pancreatic organoids to model neoplastic transformation and cancer-derived human pancreatic tumor organoids for drug testing provides new personalized approaches to modeling and treating this malignancy.

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Figure 1: Modeling pancreatic cancer with personalized human organoids.

Katie Vicari/Nature Publishing Group

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Authors and Affiliations

  1. H. Chuck Zhang and Calvin J. Kuo are in the Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, USA.,

    H Chuck Zhang & Calvin J Kuo

Authors
  1. H Chuck Zhang
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  2. Calvin J Kuo
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Corresponding author

Correspondence to Calvin J Kuo.

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Competing interests

C.J.K. is an inventor on a pending patent describing organoid culture methodologies.

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Zhang, H., Kuo, C. Personalizing pancreatic cancer organoids with hPSCs. Nat Med 21, 1249–1251 (2015). https://doi.org/10.1038/nm.3992

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