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A new Twist in kidney fibrosis

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Kidney fibrosis is a main pathological component of chronic kidney disease. Two new studies pinpoint a partial epithelial-to-mesenchymal transition as a mechanism driving the development of kidney fibrosis, thus paving the way for novel treatments of fibrosis-associated diseases.

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Figure 1: Partial EMT promotes chronic kidney disease.

Marina Corral Spence/Nature Publishing Group

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Authors and Affiliations

  1. Yossi Ovadya and Valery Krizhanovsky are in the Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.,

    Yossi Ovadya & Valery Krizhanovsky

Authors
  1. Yossi Ovadya
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  2. Valery Krizhanovsky
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Correspondence to Valery Krizhanovsky.

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The authors declare no competing financial interests.

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Ovadya, Y., Krizhanovsky, V. A new Twist in kidney fibrosis. Nat Med 21, 975–977 (2015). https://doi.org/10.1038/nm.3938

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