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Regulation of immunopathology in hepatitis B virus infection

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In the liver there is a fine balance between immune surveillance of blood-borne infections and regulation of immunopathology. A new study identifies a role for granulocytic myeloid-derived suppressor cells in limiting T cell–mediated immunopathology in hepatitis B virus infection.

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Figure 1: Dynamics of gMDSCs in chronic HBV infection.

Kim Caesar/Nature Publishing Group

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Authors and Affiliations

  1. Silvia Piconese and Vincenzo Barnaba are in the Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, and at the Istituto Pasteur-Fondazione Cenci Bolognetti, Rome, Italy.,

    Silvia Piconese & Vincenzo Barnaba

Authors
  1. Silvia Piconese
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  2. Vincenzo Barnaba
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Correspondence to Vincenzo Barnaba.

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The authors declare no competing financial interests.

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Piconese, S., Barnaba, V. Regulation of immunopathology in hepatitis B virus infection. Nat Med 21, 548–549 (2015). https://doi.org/10.1038/nm.3873

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