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Repurposing a leukocyte elastase inhibitor for neuropathic pain

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Neuropathic pain is a debilitating condition affecting millions of people worldwide. A new study investigates mechanisms of neuropathic pain initiation and identifies a promising therapeutic currently used for acute respiratory distress syndrome that may also limit acute neuropathic pain.

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Figure 1: Vicuña et al. show that upon peripheral nerve injury, T cells infiltrate the dorsal root ganglion.

Kim Caesar/Nature Publishing Group

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Authors and Affiliations

  1. Andy D. Weyer and Cheryl L. Stucky are in the department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.,

    Andy D Weyer & Cheryl L Stucky

Authors
  1. Andy D Weyer
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  2. Cheryl L Stucky
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Correspondence to Cheryl L Stucky.

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The authors declare no competing financial interests.

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Weyer, A., Stucky, C. Repurposing a leukocyte elastase inhibitor for neuropathic pain. Nat Med 21, 429–430 (2015). https://doi.org/10.1038/nm.3861

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