Frontotemporal dementia (FTD) is a neurodegenerative disease that causes social dysfunction and other symptoms. A new study suggests that social dysfunction in FTD is due to decreased microRNA-124 expression and resulting changes in glutamate receptor composition in the prefrontal cortex.
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Arrant, A., Roberson, E. MicroRNA-124 modulates social behavior in frontotemporal dementia. Nat Med 20, 1381–1383 (2014). https://doi.org/10.1038/nm.3768
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DOI: https://doi.org/10.1038/nm.3768
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