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A role for interleukin-22 in the alleviation of metabolic syndrome

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Increasing evidence points to a role for the immune system in the regulation of metabolism. Two new studies in mice indicate treatment with interleukin-22 restores mucosal immunity in diabetes and alleviates metabolic disease, resulting in improved glycemic control.

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Figure 1: The effects of IL-22.

Katie Vicari/Nature Publishing Group

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Authors and Affiliations

  1. and the Department of Biomedicine, Elise Dalmas and Marc Y. Donath are in the Clinic of Endocrinology, Diabetes and Metabolism, University of Basel, Basel, Switzerland.,

    Elise Dalmas & Marc Y Donath

Authors
  1. Elise Dalmas
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  2. Marc Y Donath
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Correspondence to Marc Y Donath.

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The authors declare no competing financial interests.

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Dalmas, E., Donath, M. A role for interleukin-22 in the alleviation of metabolic syndrome. Nat Med 20, 1379–1381 (2014). https://doi.org/10.1038/nm.3748

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