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A local circadian clock calls time on lung inflammation

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Inflammatory diseases typically display circadian variation in symptom severity. A new study in mice shows how a pulmonary epithelial cell clock controls neutrophil recruitment to the lungs and provides insight into interactions between local and systemic circadian clocks.

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Figure 1: The pulmonary clock and inflammatory responses.

Debbie Maizels/Nature Publishing Group

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Authors and Affiliations

  1. Department of Infection and Immunity, A.A. Roger Thompson, Sarah R. Walmsley & Moira K.B. Whyte are in the Academic Unit of Respiratory Medicine, The Medical School, University of Sheffield, Sheffield, UK.,

    A A Roger Thompson, Sarah R Walmsley & Moira K B Whyte

Authors
  1. A A Roger Thompson
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  2. Sarah R Walmsley
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  3. Moira K B Whyte
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Correspondence to Moira K B Whyte.

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The authors declare no competing financial interests.

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Thompson, A., Walmsley, S. & Whyte, M. A local circadian clock calls time on lung inflammation. Nat Med 20, 809–811 (2014). https://doi.org/10.1038/nm.3649

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