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The long reach of liver transplantation

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Figure 1: Three early approaches to liver transplantation.
Figure 2: Early successes of liver transplantation.
Figure 3: Stepwise immunosuppression-associated improvements in liver-transplant survival.
Figure 4
Figure 5: The kinetics of immunosuppression-aided exhaustion and deletion of host-versus-graft (HvG) and graft-versus-host (GvH) responses occurring contemporaneously in organ recipients after migration of the graft's passenger leukocytes.

References

  1. Starzl, T.E., Kaupp, H.A. Jr., Brock, D.R., Lazarus, R.E. & Johnson, R.V. Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow. Surg. Gynecol. Obstet. 111, 733–743 (1960).

    PubMed Central  Google Scholar 

  2. Starzl, T.E., Kaupp, H.A. Jr., Brock, D.R., Butz, G.W. Jr. & Linman, J.W. Homotransplantation of multiple visceral organs. Am. J. Surg. 103, 219–229 (1962).

    Article  CAS  Google Scholar 

  3. Starzl, T.E. et al. The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood. Surg. Gynecol. Obstet. 137, 179–199 (1973).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Starzl, T.E. et al. Homotransplantation of the liver in humans. Surg. Gynecol. Obstet. 117, 659–676 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Starzl, T.E. et al. Orthotopic homotransplantation of the human liver. Ann. Surg. 168, 392–415 (1968).

    Article  CAS  Google Scholar 

  6. Starzl, T.E. Experience in Hepatic Transplantation (WB Saunders Company, Philadelphia, PA, 1969).

    Google Scholar 

  7. Starzl, T.E., Klintmalm, G.B.G., Porter, K.A., Iwatsuki, S. & Schroter, G.P.J. Liver transplantation with use of cyclosporin A and prednisone. N. Engl. J. Med. 305, 266–269 (1981).

    Article  CAS  Google Scholar 

  8. Starzl, T.E. et al. FK 506 for human liver, kidney and pancreas transplantation. Lancet 334, 1000–1004 (1989).

    Article  Google Scholar 

  9. Starzl, T.E. et al. Cell migration, chimerism, and graft acceptance. Lancet 339, 1579–1582 (1992).

    Article  CAS  Google Scholar 

  10. Starzl, T.E. & Zinkernagel, R. Antigen localization and migration in immunity and tolerance. N. Engl. J. Med. 339, 1905–1913 (1998).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Thomas E. Starzl is Director Emeritus, Thomas E. Starzl Transplantation Institute, Professor of Surgery, Distinguished Service Professor, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.,

    Thomas E Starzl

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  1. Thomas E Starzl
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Correspondence to Thomas E Starzl.

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Starzl, T. The long reach of liver transplantation. Nat Med 18, 1489–1492 (2012). https://doi.org/10.1038/nm.2927

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