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Skin function for human CD1a-reactive T cells

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Human CD4+ T cells that produce interleukin 22 are an essential component of skin defense and repair. New evidence shows that these T cells recognize CD1a-lipid complexes on Langerhans cells.

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Figure 1: CD1-reactive CD4+ T cells.

Marina Corral

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Authors and Affiliations

  1. Marco Colonna is in the Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.,

    Marco Colonna

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  1. Marco Colonna
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Correspondence to Marco Colonna.

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Colonna, M. Skin function for human CD1a-reactive T cells. Nat Immunol 11, 1079–1080 (2010). https://doi.org/10.1038/ni1210-1079

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