Jim Gowans opened a new era of immunology by combining physiological in vivo studies with prospective enrichment of small lymphocytes, validating the clonal selection theory, discovering lymphocyte homing and recirculation, and training others to follow.
This is a preview of subscription content, log in via an institution to check access.
References
Weissman, I.L. Immunol. Rev. 185, 159–174 (2002).
Burnet, F.M. The Clonal Selection Theory of Acquired Immunology (Cambridge University Press, London, 1959).
Mitchison, N.A. & Dube, O.L. J. Exp. Med. 102, 179 (1955).
Maximow, A. Folia Haematol. (Leipzig) 8, 125–141 (1909).
Gowans, J.L. Ann. NY Acad. Sci. 99, 432–455 (1962).
Gowans, J.L. J. Physiol. (Lond.) 146, 54–69 (1959).
Gowans, J.L., McGregor, D.D., Cowen, D.M. & Ford, C.E. Nature 196, 651–655 (1962).
McGregor, D.D. & Gowans, J.L. J. Exp. Med. 117, 303–320 (1963).
Gowans, J.L. & Knight, E.J. Proc. R. Soc. Lond. B 159, 257–282 (1964).
Marchesi, V.T. & Gowans, J.L. Proc. R. Soc. Lond. B 159, 283–290 (1964).
Ford, W.L. & Gowans, J.L. Proc. R. Soc. Lond. B 168, 244–262 (1967).
McGregor, D.D., McCullagh, P.J. & Gowans, J.L. Proc. R. Soc. Lond. B 168, 229–243 (1967).
Gowans, J.L. & Uhr, J.W. J. Exp. Med. 124, 1017–1030 (1966).
Rowley, D.A., Gowans, J.L., Ford, W.L., Atkins, R.C. & Smith, M.E. J. Exp. Med. 136, 499–513 (1972).
Ellis, S.T. & Gowans, J.L. Proc. R. Soc. Lond. B 183, 125–139 (1973).
Dutton, R.W. & Mishell, R.I. J. Exp. Med. 126, 443–454 (1967).
Taylor, R.B., Duffus, W.P.H., Raff, M.C. & dePetris, S. Nat. New Biol. 233, 225–229 (1971).
de Petris, S. & Raff, M.C. Eur. J. Immunol. 2, 523–535 (1972).
Weissman, I.L. J. Exp. Med. 126, 291–304 (1967).
Weissman, I.L. J. Exp. Med. 137, 504–510 (1973).
Butcher, E.C., Scollay, R.G. & Weissman, I.L. Eur. J. Immunol. 10, 556–561 (1980).
Gallatin, W.M., Weissman, I.L. & Butcher, E.C. Nature 304, 30–34 (1983).
Gallatin, M. et al. Cell 44, 673–680 (1986).
Siegelman, M., van de Rijn, M. & Weissman, I.L. Science 243, 1165–1172 (1989).
Holzmann, B., McIntyre, B.W. & Weissman, I.L. Cell 56, 37–46 (1989).
Parrott, D.M.V., DeSousa, M.A.B. & East, J. J. Exp. Med. 123, 191–204 (1966).
Gutman, G.A. & Weissman, I.L. Immunology 23, 465–479 (1972).
Weissman, I.L., Warnke, R., Butcher, E., Rouse, R. & Levy, R. Hum. Pathol. 9, 25–45 (1978).
Muller–Sieburg, C., Whitlock, C.A. & Weissman, I.L. Cell 44, 653–662 (1986).
Spangrude, G.J., Heimfeld, S. & Weissman, I.L. Science 241, 58–62 (1988).
Baum, C.M., Weissman, I.L., Tsukamoto, A.S., Buckle, A. & Peault, B. Proc. Natl. Acad. Sci. USA 89, 2804–2808 (1992).
Uchida, N. et al. Proc. Natl. Acad. Sci. USA 97, 14720–14725 (2000).
Sherwood, R.I. et al. Cell 119, 543–554 (2004).
Chan, C.K. et al. Nature 457, 490–494 (2009).
Miyamoto, T., Weissman, I.L. & Akashi, K. Proc. Natl. Acad. Sci. USA 97, 7521–7526 (2000).
Jamieson, C.H. et al. N. Engl. J. Med. 351, 657–667 (2004).
Passegue, E., Wagner, E.F. & Weissman, I.L. Cell 119, 431–443 (2004).
Jamieson, C.H. et al. Proc. Natl. Acad. Sci. USA 103, 6224–6229 (2006).
Prince, M.E. et al. Proc. Natl. Acad. Sci. USA 104, 973–978 (2007).
Majeti, R. et al. Proc. Natl. Acad. Sci. USA 106, 3396–3401 (2009).
Abrahamsson, A.E. et al. Proc. Natl. Acad. Sci. USA 106, 3925–3929 (2009).
Chan, K.S. et al. Proc. Natl. Acad. Sci. USA 106, 14016–14021 (2009).
Silverstein, A.M. Nat. Immunol. 2, 569–571 (2001).
Miller, J.F.A.P. Nat. Immunol. 2, 981–982 (2001).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
I.W. owns Amgen stock and is a director and consultant for Stem Cells.
Rights and permissions
About this article
Cite this article
Weissman, I. Lymphocytes, Jim Gowans and in vivo veritas. Nat Immunol 11, 1073–1075 (2010). https://doi.org/10.1038/ni1210-1073
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni1210-1073
- Springer Nature America, Inc.
This article is cited by
-
The early history of Stanford Immunology
Immunologic Research (2014)