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CCR5 and its ligands: a new axis of evil?

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Many additional effects in HIV pathogenesis are now described for the chemokine receptor CCR5, long recognized as an important coreceptor for HIV, and its ligand CCL3L1.

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Figure 1: The CCR5-CCL3L1 axis in HIV pathogenesis and in health.

Kim Caesar

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Authors and Affiliations

  1. Michael M. Lederman and Scott F. Sieg are with the Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA. mxl6@case.edu,

    Michael M Lederman & Scott F Sieg

Authors
  1. Michael M Lederman
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  2. Scott F Sieg
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Lederman, M., Sieg, S. CCR5 and its ligands: a new axis of evil?. Nat Immunol 8, 1283–1285 (2007). https://doi.org/10.1038/ni1207-1283

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  • DOI: https://doi.org/10.1038/ni1207-1283

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