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Positive selection in a Schnurri

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Regulation of the transcription factor Shn-2 by signals emanating from the TCR can distinguish positive from negative selection of developing thymocytes.

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Figure 1: Highly simplified Dpp and TGF-β superfamily signaling pathways.

Bob Crimi

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  1. Department of Immunology, IMM1, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, 92037, CA, USA

    Nicholas R. J. Gascoigne

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  1. Nicholas R. J. Gascoigne
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Gascoigne, N. Positive selection in a Schnurri. Nat Immunol 2, 989–991 (2001). https://doi.org/10.1038/ni1101-989

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