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Sensing necrosis with Mincle

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The mechanisms that lead to inflammation after necrotic cell death are poorly understood. New data show that the C-type lectin Mincle is involved in this process.

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Figure 1: The C-type lectin receptor Mincle triggers inflammatory responses to necrotic cells.

Kim Casear

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Authors and Affiliations

  1. Division of Immunology, Gordon D. Brown is with the Institute of Infectious Disease and Molecular Medicine, Clinical Laboratory Sciences, University of Cape Town, Observatory 7925, Cape Town, South Africa. gordon.brown@mweb.co.za,

    Gordon D Brown

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  1. Gordon D Brown
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Brown, G. Sensing necrosis with Mincle. Nat Immunol 9, 1099–1100 (2008). https://doi.org/10.1038/ni1008-1099

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