The establishment and replenishment of thymic epithelium and the persistence of epithelial progenitor cells into adult life were discussed at ThymOz-V 2006.
References
Sutherland, J. et al. J. Immunol. 175, 2741–2753 (2005).
Young, H.E. et al. J. Cell. Mol. Med. 9, 753–769 (2005).
Gill, J., Malin, M., Hollander, G.A. & Boyd, R. Nat. Immunol. 3, 635–642 (2002).
Bennett, A.R. et al. Immunity 16, 803–814 (2002).
Nijhof, J. et al. Development 133, 3027–3037 (2006).
Clark, R.A., Yamanaka, K., Bai, M., Dowgiert, R. & Kupper, T.S. J. Clin. Invest. 115, 3239–3249 (2005).
Naquet, P., Naspetti, M. & Boyd, R. Semin. Immunol. 11, 47–56 (1999).
Blackburn, C. & Manley, N. Nat. Rev. Immunol. 4, 278–289 (2004).
Suniara, R.K., Jenkinson, E.J. & Owen, J.J.T. J. Exp. Med. 191, 1051–1056 (2000).
Patel, S.R., Gordon, J., Mahbub, F., Blackburn, C.C. & Manley, N.R. Gene Expr. Patterns, published online 3 March 2006 (doi:10.1016/j.modgep.2006.01.011).
Gordon, J., Bennett, A.R., Blackburn, C.C. & Manley, N.R. Mech. Dev. 103, 141–143 (2001).
Masuda, K. et al. EMBO J. 24, 4052–4060 (2005).
Gray, D.H. et al. Blood, published online 8 August 2006 (doi:10.1182/blood-2006-02-004531).
Rossi, F. et al. Nat. Immunol. 6, 626–634 (2005).
Heng, T.S., Goldberg, G.L., Gray, D.H., Sutherland, J.S., Chidgey, A.P. & Boyd, R.L. J. Immunol. 175, 2982–2993 (2005).
Goldberg, G.L. et al. Transplantation 80, 1604–1613 (2005).
Ritter, M.A. & Boyd, R.L. Immunol. Today 14, 462–469 (1993).
Ropke, C., Van Soest, P., Platenburg, P.P. & Van Ewijk, W. Dev. Immunol. 4, 149–156 (1995).
Rossi, S.W., Jenkinson, W.E., Anderson, G. & Jenkinson, E.J. Nature 441, 988–991 (2006).
Gordon, J. et al. Nat. Immunol. 5, 546–553 (2004).
Rodewald, H.R., Paul, S., Haller, C., Bluethmann, H. & Blum, C. Nature 414, 763–768 (2001).
Gillard, G.O. & Farr, A.G. J. Immunol. 176, 5815–5824 (2006).
Bleul, C.C., Corbeaux, T., Reuter, A., Fisch, P., Monting, J.S. & Boehm, T. Nature 441, 992–996 (2006).
Muller, S.M. et al. Proc. Natl. Acad. Sci. USA 102, 10587–10592 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chidgey, A., Boyd, R. Stemming the tide of thymic aging. Nat Immunol 7, 1013–1016 (2006). https://doi.org/10.1038/ni1006-1013
Issue Date:
DOI: https://doi.org/10.1038/ni1006-1013
- Springer Nature America, Inc.
This article is cited by
-
Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
Nature Reviews Immunology (2008)