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Dead man walking: how thymocytes scan the medulla

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The thymic medulla provides a unique milieu for the induction of T cell tolerance. New work now provides a first glimpse of how thymocytes scan this microenvironment and thus maximize their chances of encountering self antigen.

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Figure 1: Linking the topology and timing of T cell development with thymocyte motility.

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  1. Ludger Klein is with the Institute for Immunology, Ludwig-Maximilian-University, Munich, Germany. ludger.klein@med.lmu.de,

    Ludger Klein

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  1. Ludger Klein
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Klein, L. Dead man walking: how thymocytes scan the medulla. Nat Immunol 10, 809–811 (2009). https://doi.org/10.1038/ni0809-809

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