The mechanisms governing natural killer cell development are not well understood. Activation of the tyrosine kinase receptors Tyro3, Axl and Mer on pre–natural killer cells by stromal cell–produced ligands now seems to be critical.
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Walzer, T., Vivier, E. NK cell development: Gas matters. Nat Immunol 7, 702–704 (2006). https://doi.org/10.1038/ni0706-702
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DOI: https://doi.org/10.1038/ni0706-702
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