Successful microarray experimentation can generate enormous amounts of data, potentially very rich but also very unwieldy. Bold outlooks and new methods for data analysis and presentation should yield additional insight into the complexities of the immune system.
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Acknowledgements
We thank D. Laidlaw, J.J. Collins and D. Koller for discussions; E. Hyatt, Q.M. Pham, G. Losyev, R. Saccone and J. Johnson for assistance with mice, cell sorting and microarray processing; and the S+ Listserv members for advice. Supported by the National Institutes of Health (AR046580, AI51530, AI52343, DK60027, DK59658 to C.B. and D.M.) and the William T. Young Chair.
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Hyatt, G., Melamed, R., Park, R. et al. Gene expression microarrays: glimpses of the immunological genome. Nat Immunol 7, 686–691 (2006). https://doi.org/10.1038/ni0706-686
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DOI: https://doi.org/10.1038/ni0706-686
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