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The origin of dendritic cells

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Dendritic cells are specialized in antigen presentation to lymphocytes. New research clarifies the origin and kinetics of differentiation of a subset of dendritic cells in the spleen and lymph nodes.

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Figure 1: The origin, lifespan and turnover rate of macrophages and DCs in steady-state conditions or during inflammation and infection.

Kim Caesar

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Authors and Affiliations

  1. Frederic Geissmann is with the Institut National de la Santé et de la Recherche Médicale U838, Hôpital Necker-Enfants Malades, Faculté de médecine de l'Université Paris Descartes, Paris 75105, France. geissmann@necker.fr,

    Frederic Geissmann

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  1. Frederic Geissmann
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The author declares no competing financial interests.

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Geissmann, F. The origin of dendritic cells. Nat Immunol 8, 558–560 (2007). https://doi.org/10.1038/ni0607-558

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