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Killing some to make way for others

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Limited niche availability restricts the number of long-lived plasma cells that can reside in the bone marrow. New research describes homeostatic regulatory mechanisms that allow newly 'minted' plasma cells to gain entry to such niches.

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Figure 1: Different modes of inhibitory signaling by FcγRIIb on follicular B cells and plasma cells.

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Authors and Affiliations

  1. Jeffrey V. Ravetch is in the Laboratory of Molecular Genetics and Immunology and Michel Nussenzweig is in the Laboratory of Molecular Immunology, Rockefeller University, New York, New York 10021, USA. ravetch@mail.rockefeller.edu,

    Jeffrey V Ravetch & Michel Nussenzweig

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  1. Jeffrey V Ravetch
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  2. Michel Nussenzweig
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Ravetch, J., Nussenzweig, M. Killing some to make way for others. Nat Immunol 8, 337–339 (2007). https://doi.org/10.1038/ni0407-337

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