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Class II peptide multimers: promise for type 1A diabetes?

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Lack of proper tools hampers early diagnosis and treatment of antigen-specific autoimmune diseases. A new strategy that makes use of peptide-MHC reagents could control recent-onset diabetes in mice.

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Figure 1: MHC class II–peptide multimers.

Bob Crimi

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Eisenbarth, G., Nepom, G. Class II peptide multimers: promise for type 1A diabetes?. Nat Immunol 3, 344–345 (2002). https://doi.org/10.1038/ni0402-344

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