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Epithelial cell microRNAs in gut immunity

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MicroRNAs regulate many biological functions. Research now indicates that intestinal epithelial microRNAs might also regulate the differentiation of goblet cells and promote T helper type 2 immune responses to parasite infection.

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Figure 1: MicroRNAs regulate intestinal epithelial differentiation and TH2 immune responses.

Katie Vicari

References

  1. Biton, M. et al. Nat. Immunol. 12, 239–246 (2011).

    Article  CAS  Google Scholar 

  2. van der Flier, L.G. & Clevers, H. Annu. Rev. Physiol. 71, 241–260 (2009).

    Article  CAS  Google Scholar 

  3. Rimoldi, M. et al. Nat. Immunol. 6, 507–514 (2005).

    Article  CAS  Google Scholar 

  4. Dahan, S., Roth-Walter, F., Arnaboldi, P., Agarwal, S. & Mayer, L. Immunol. Rev. 215, 243–253 (2007).

    Article  CAS  Google Scholar 

  5. Atarashi, K. et al. Science 331, 337–341 (2011).

    Article  CAS  Google Scholar 

  6. Gaboriau-Routhiau, V. et al. Immunity 31, 677–689 (2009).

    Article  CAS  Google Scholar 

  7. Ivanov, I.I. et al. Cell 139, 485–498 (2009).

    Article  CAS  Google Scholar 

  8. Maizels, R.M., Pearce, E.J., Artis, D., Yazdanbakhsh, M. & Wynn, T.A. J. Exp. Med. 206, 2059–2066 (2009).

    Article  CAS  Google Scholar 

  9. Bartel, D.P. Cell 116, 281–297 (2004).

    Article  CAS  Google Scholar 

  10. McKenna, L.B. et al. Gastroenterology 139, 1654–1664, (2010).

    Article  CAS  Google Scholar 

  11. Wu, F. et al. Inflamm. Bowel Dis. 16, 1729–1738 (2010).

    Article  Google Scholar 

  12. Ishikawa, N. et al. Gastroenterology 113, 542–549 (1997).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Yoshiyuki Goto and Hiroshi Kiyono are in the Division of Mucosal Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.,

    Yoshiyuki Goto & Hiroshi Kiyono

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  1. Yoshiyuki Goto
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  2. Hiroshi Kiyono
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Correspondence to Hiroshi Kiyono.

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The authors declare no competing financial interests.

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Goto, Y., Kiyono, H. Epithelial cell microRNAs in gut immunity. Nat Immunol 12, 195–197 (2011). https://doi.org/10.1038/ni0311-195

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