Skip to main content
SpringerLink
Log in

Lymphoid development: it's not 'all Greek to us' any more

  • Meeting Report
  • Published:

From Nature Immunology

View current issue Submit your manuscript

Lymphocyte lineage specification involves multiple regulatory factors that act in reciprocal fashion to ensure lineage committment and identity. New insights on how these factors interact were presented at the second Aegean Workshop on Gene Regulation in Lymphocyte Development.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: The lymphocyte development workshop was held near the ancient Minoan ruins of Knossos, located on the Greek island of Crete.
Figure 2: Molecular events involved in B and T lineage specification and commitment.
Figure 3: Transcriptional control of mature lymphocyte cell fates.

References

  1. Okada, A. & Alt, F.W. Semin. Immunol. 6, 185–196 (1994).

    Article  CAS  Google Scholar 

  2. Kondo, M., Weissman, I.L. & Akashi, K. Cell 91, 661–672 (1997).

    Article  CAS  Google Scholar 

  3. Allman, D. et al. Nat. Immunol. 4, 168–174 (2003).

    Article  CAS  Google Scholar 

  4. Schwarz, B.A. & Bhandoola, A. Nat. Immunol. 5, 953–960 (2004).

    Article  CAS  Google Scholar 

  5. Radtke, F. et al. Immunity 10, 547–558 (1999).

    Article  CAS  Google Scholar 

  6. Pui, J.C. et al. Immunity 11, 299–308 (1999).

    Article  CAS  Google Scholar 

  7. Porritt, H.E. et al. Immunity 20, 735–745 (2004).

    Article  CAS  Google Scholar 

  8. Quong, M.W., Romanow, W.J. & Murre, C. Annu. Rev. Immunol. 20, 301–322 (2002).

    Article  CAS  Google Scholar 

  9. Smith, E. & Sigvardsson, M. J. Leukoc. Biol. 75, 973–981 (2004).

    Article  CAS  Google Scholar 

  10. Nutt, S.L., Heavey, B., Rolink, A.G. & Busslinger, M. Nature 401, 556–562 (1999).

    Article  CAS  Google Scholar 

  11. Rolink, A., Nutt, S.L., Melchers, F. & Busslinger, M. Nature 401, 603–606 (1999).

    Article  CAS  Google Scholar 

  12. Miller, J.P. et al. J. Exp. Med. 196, 705–711 (2002).

    Article  CAS  Google Scholar 

  13. Logan, C.Y. & Nusse, R. Annu. Rev. Cell Dev. Biol. 20, 781–810 (2004).

    Article  CAS  Google Scholar 

  14. Schubart, D.B., Rolink, A., Kosco-Vilbois, M.H., Botteri, F. & Matthias, P. Nature 383, 538–542 (1996).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Veterinary & Animal Sciences, University of Massachusetts, Amherst, 01003, Massachusetts, USA

    Barbara A Osborne

  2. Department of Pathology and Committees on Immunology Cancer Biology and Developmental Biology, University of Chicago, Chicago, 60637, Illinois, USA

    Barbara L Kee

Authors
  1. Barbara A Osborne
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Barbara L Kee
    View author publications

    You can also search for this author in PubMed Google Scholar

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Cite this article

Osborne, B., Kee, B. Lymphoid development: it's not 'all Greek to us' any more. Nat Immunol 6, 119–123 (2005). https://doi.org/10.1038/ni0205-119

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ni0205-119

  • Springer Nature America, Inc.

Search

Navigation