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Friendly and dangerous signals: is the tissue in control?

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In their own defense, tissues send a panoply of signals that initiate immunity and guide the choice of effector class. TH1-TH2 and Treg is far too simple a representation of the breathtaking variety of the resulting responses.

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Authors and Affiliations

  1. The Ghost Lab, Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, 20892, Maryland, USA

    Polly Matzinger

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  1. Polly Matzinger
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Matzinger, P. Friendly and dangerous signals: is the tissue in control?. Nat Immunol 8, 11–13 (2007). https://doi.org/10.1038/ni0107-11

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  • DOI: https://doi.org/10.1038/ni0107-11

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