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ComPPARtmentalizing NF-κB in the gut

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How do commensal gut bacteria coexist with the host without causing uncontrolled inflammation? The answer may lie in the induction of the association of PPAR-γ with NF-κB.

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Figure 1: In the typical response to microbial pathogens (green), bacterial components are recognized by TLRs.

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Beg, A. ComPPARtmentalizing NF-κB in the gut. Nat Immunol 5, 14–16 (2004). https://doi.org/10.1038/ni0104-14

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