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Trained macrophages support hygiene hypothesis

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Replacement of resident alveolar macrophages by monocyte-derived macrophages after herpesvirus infection protects against asthma.

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Figure 1: Herpesvirus infection induces persisting changes in alveolar macrophages that protect against asthma.

Kim Caesar/Springer Nature

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Authors and Affiliations

  1. Centre d'Immunologie de Marseille-Luminy, Aix Marseille University, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Marseille, France

    Bérengère de Laval & Michael H Sieweke

  2. Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtzgemeinschaft, Berlin, Germany

    Michael H Sieweke

Authors
  1. Bérengère de Laval
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  2. Michael H Sieweke
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Correspondence to Michael H Sieweke.

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The authors declare no competing financial interests.

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de Laval, B., Sieweke, M. Trained macrophages support hygiene hypothesis. Nat Immunol 18, 1279–1280 (2017). https://doi.org/10.1038/ni.3874

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